Healthcare ETFs give traders publicity to a defensive nook of the market – one that’s more likely to profit from constant demand and rising costs over the long run.
In keeping with the Facilities for Medicare and Medicaid Companies, nationwide healthcare expenditures accounted for greater than 17% of U.S. gross home product (GDP) in 2019. Trying ahead, these expenditures are projected to develop at a median annual price of 5.4% via 2028 to succeed in $6.2 trillion. By then, healthcare bills are anticipated to account for roughly 20% of your entire financial output.
As residents and shoppers, there are many causes for outrage over the ever-increasing prices of American healthcare. Working example: The Commonwealth Fund’s latest rating of developed economies discovered the U.S. has the worst healthcare amongst main developed nations regardless of spending considerably extra on medical care.
However as an investor, it is price noting the alternatives right here. In any case, our for-profit system continues to offer large income for drugmakers, hospital operators, insurers and others. And as a substitute of placing all of your eggs in a single basket, healthcare ETFs enable traders to diversify throughout a gaggle of shares or industries.
That mentioned, listed below are 11 high healthcare ETFs to purchase now. It is a large choice of exchange-traded funds that meet a number of totally different funding targets.
Have a look.
Information is as of Aug. 31. Dividend yields characterize the trailing 12-month yield, which is a typical measure for fairness funds.

Well being Care Choose Sector SPDR Fund
- Belongings underneath administration: $33.7 billion
- Dividend yield: 1.3%
- Bills: 0.12%, or $12 yearly for each $10,000 invested
The largest healthcare ETF by property at current is the State Avenue World Advisors’ Well being Care Choose Sector SPDR Fund (XLV, $135.21). XLV is the best and most liquid option to play the most important healthcare shares on Wall Avenue.
The 60 or so holdings on this fund are a easy itemizing of the healthcare shares which are current within the broader S&P 500 Index. These firms are then weighted by measurement, so acquainted names like Johnson & Johnson (JNJ), UnitedHealth Group (UNH) and Pfizer (PFE) high the listing of elements.
The deal with huge shares implies that the portfolio is a bit top-heavy, nevertheless. To the purpose: About 22% of all property are behind these three shares alone.
In fact, many traders use sector funds to pay attention their holdings into one space of the market. So the truth that XLV is not hyper-diversified won’t be a dealbreaker for traders merely trying to play probably the most outstanding healthcare shares through an ETF.
Be taught extra about XLV on the State Avenue World Advisors supplier web site.

Vanguard Healthcare ETF
- Belongings underneath administration: $16.9 billion
- Dividend yield: 1.1%
- Bills: 0.10%
Additionally well-liked with about $17 billion in whole property underneath administration is the Vanguard Healthcare ETF (VHT, $262.49). This fund is much like the main XLV providing in some ways, as its high three holdings are the identical quick listing of mega-cap healthcare shares. Nonetheless, it’s far more diversified, with a deep bench of about 500 whole shares making up its lineup.
To be clear, it is nonetheless a bit top-heavy, because the 10 main positions collectively account for roughly 40% of your entire portfolio at current, regardless of there being a whole bunch of different particular person positions. Nonetheless, these small stakes in lesser-known medical machine and biotechnology shares can nonetheless present huge returns if and once they take off.
Then again, if these smaller shares underperform, then the healthcare ETF may be held again. That is really what has occurred recently, too, as this Vanguard fund is “solely” up about 17% in 2021 to date – lower than the roughly 20% features for XLV and the broader S&P 500 in the identical interval. Nonetheless, that is not too shabby of a return.
Be taught extra about VHT on the Vanguard supplier web site.

iShares Biotechnology ETF
- Belongings underneath administration: $11.Three billion
- Dividend yield: 0.2%
- Bills: 0.45%
The iShares Biotechnology ETF (IBB, $172.28) was not too long ago highlighted as the most effective biotech funds to play within the higher-volatility area. IBB is the chief amongst funds on this dynamic subset of healthcare shares.
The fund has about $11 billion in property underneath administration. And it is a one-stop store for many who need to deal with firms which are aggressively researching the subsequent technology of cures for illnesses like most cancers and Alzheimer’s that, as of but, do not have dependable therapies.
With about 270 positions, IBB offers traders publicity to development-stage biotechs which are unprofitable as of but and are banking on future Meals and Drug Administration (FDA) approvals to show their worth to traders. That makes this fund riskier than the standard large-cap healthcare ETF that’s counting on entrenched insurance coverage companies and Massive Pharma mainstays.
That mentioned, IBB is well-liked partly as a result of its high holdings at current embrace Moderna (MRNA), Amgen (AMGN) and Gilead Sciences (GILD) – three very mature and really worthwhile biotech firms that collectively add as much as greater than $370 billion in market worth. This supplies a great basis for the smaller and extra aggressive picks that complement the portfolio of this healthcare ETF.
Be taught extra about IBB on the iShares supplier web site.

ARK Genomic Revolution ETF
- Belongings underneath administration: $8.5 billion
- Dividend yield: 0.00%
- Bills: 0.75%
In fact, some traders aren’t involved in lowering their danger profile by reliance on a few of the bigger biotech shares on the market. In contrast, they merely need an aggressive and tactical play on small startups researching doubtlessly groundbreaking therapies.
That is what the ARK Genomic Revolution ETF (ARKG, $85.68) supplies, with about 50 holdings which are all concerned in next-gen healthcare know-how together with bioinformatics, molecular diagnostics and stem cell analysis.
Proper now, the lineup is led by distant medication and diagnostics innovator Teladoc Well being (TDOC), DNA analysis agency Pacific Biosciences of California (PACB) and most cancers drug developer Destiny Therapeutics (FATE).
These are all names that veteran biotech merchants could know nicely, however the typical investor is probably not aware of. That proves the ability of ARKG to establish off-the-beaten-path healthcare names as a substitute of the identical outdated lineup of blue-chip shares it’s possible you’ll have already got publicity to in your portfolio.
ARKG has struggled a bit recently, and is at the moment within the crimson this yr as a few of these extra aggressive picks in its portfolio have declined. Long run, it stays up a formidable 170% within the final two years and 40% previously 12 months. Traders who can abdomen the short-term volatility should need to give this high-octane healthcare ETF a glance.
Be taught extra about ARKG on the Ark Make investments supplier web site.

iShares U.S. Medical Units ETF
- Belongings underneath administration: $8.6 billion
- Dividend yield: 0.2%
- Bills: 0.41%
One other option to slice up the universe of healthcare shares is to keep away from drugmakers of any measurement and as a substitute to deal with medical gadgets. This may be accomplished through the iShares U.S. Medical Units ETF (IHI, $65.58).
Whereas high-profile branded cures can generate huge bucks underneath patent safety, some Massive Pharma firms have been underneath stress in recent times after these medicine grew to become accessible via cheaper generic prescriptions.
Throw in continued criticism from many in Washington about what is typically seen as price-gouging on life-saving drugs and traders could need to take into account options to banking on huge margins from huge pharmaceutical companies.
Medical gadgets are an attention-grabbing center floor. Right here, producers of high-tech surgical gear or coronary heart valves can nonetheless command huge revenue margins at the same time as they produce the fairly mundane artifacts of the healthcare system that may embrace every thing from IV tubes to examination gloves.
IHI’s high positions amongst its 60-something holdings at current embrace insertable coronary heart monitor maker Abbott Laboratories (ABT), specialty diagnostics agency Thermo Fisher Scientific (TMO) and mobile evaluation specialist Danaher (DHR). The healthcare fund is admittedly fairly targeted on this trio, with 36% of all property within the three positions, however they’re entrenched and steady methods to play the sector with out worrying about drug patent expirations.
Be taught extra about IHI on the iShares supplier web site.

SPDR S&P Well being Care Gear ETF
- Belongings underneath administration: $828.Zero million
- Dividend yield: 0.00%
- Bills: 0.35%
The SPDR S&P Well being Care Gear ETF (XHE, $130.96) gives a barely extra balanced strategy to the healthcare sector and not using a deal with Massive Pharma.
Although smaller at simply $828 million in whole property, its “equal weight” strategy to medical gadgets and associated gear ensures that the 85-odd holdings are all just about on equal footing.
Working example: Whilst you’ll discover Danaher as a high holding but once more, it is solely at 1.6% of whole property proper now – consistent with many of the different firms on the listing, together with $2.Eight billion veterinary medication supplier Heska (HSKA), which actually would not pop up on the standard listing of large-cap healthcare shares.
As a result of the money is unfold round in lots of locations, XHE has barely lagged the broader S&P 500 Index for the yr to this point (15% vs. 20%). Nonetheless, it is plain that in a bout of volatility for a choose group of shares, it’s your decision the diversification of this healthcare ETF in your facet.
Be taught extra about XHE on the iShares supplier web site.

iShares World Healthcare ETF
- Belongings underneath administration: $3.5 billion
- Dividend yield: 1.1%
- Bills: 0.43%
To this point, the healthcare ETFs on this listing have had a decidedly home focus. However the iShares World Healthcare ETF (IXJ, $88.36) is a well-liked different for those who need to play worldwide healthcare developments and never simply the U.S. market.
This is a crucial differentiator as a result of many shares that traders are aware of as healthcare shoppers could not really be headquartered within the U.S. As such, they might be excluded from the standard home index fund just because these multinational firms are headquartered abroad.
To be clear, this isn’t a totally worldwide fund and high U.S. firms together with Johnson & Johnson nonetheless lead the listing. Nonetheless, Swiss drugmaker Roche Holding (RHHBY) and French pharmaceutical agency Sanofi (SNY) even have outstanding spots on this portfolio.
Massive Pharma shares make up a big share of the portfolio, and collectively the pharma, biotech and life sciences industries account for about 60% of whole property. Nonetheless, it is plain that this added degree of worldwide diversification offers a extra fulsome illustration of the sector than only a U.S.-only healthcare ETF.
Be taught extra about IXJ on the iShares supplier web site.

First Belief Well being Care AlphaDEX Fund
- Belongings underneath administration: $1.6 billion
- Dividend yield: 0.00%
- Bills: 0.61%
The First Belief Well being Care AlphaDEX Fund (FXH, $125.52) gives a novel strategy to investing in healthcare. FXJ is an actively managed healthcare ETF that appears on the universe of huge and mid-sized shares within the sector after which focuses on those its managers suppose have probably the most potential.
The precise methodology behind FXH is proprietary, but it surely includes rating healthcare shares primarily based on particular elements, together with short-term and long-term worth momentum, progress metrics like income enlargement and worth metrics together with ebook worth. Then it takes the shares that meet its highest standards, which proper now provides as much as about 85 whole holdings.
The result’s an eclectic lineup that at the moment consists of high-flying biotech Moderna alongside lesser-known diagnostics agency Bio-Rad Laboratories (BIO) and surgical merchandise maker Hologic (HOLX). This deal with the crème de la crème has allowed FXH to tack on 17% or so in 2021 to outperform a number of of the opposite healthcare ETFs on this listing.
Nonetheless, understand that whereas the opposite healthcare ETFs right here are typically a basic play on a particular pattern, this fund may be very a lot reliant on the screening methodology. That might be good or might be unhealthy, relying on what shares get spit out every quarter.
Be taught extra about FXH on the First Belief supplier web site.

Invesco Dynamic Prescription drugs ETF
- Belongings underneath administration: $454.9 million
- Dividend yield: 0.7%
- Bills: 0.56%
The Invesco Dynamic Prescription drugs ETF (PJP, $82.17) is one other actively managed healthcare ETF. PJP relies by itself proprietary screening methodology, which incorporates worth momentum, earnings momentum and worth metrics.
The fund includes simply 23 U.S. pharmaceutical firms. Nonetheless, the definition of “pharma” is fairly broad and consists of any publicly traded inventory engaged within the analysis, manufacture or sale of medicine of any kind.
That offers a reasonably good mixture of entrenched drugmakers like AbbVie (ABBV) and Gilead Sciences, which at the moment high the listing of holdings with weightings of about 6% apiece. Farther down the listing, you will additionally discover small drug firms just like the $1.5 billion Supernus Prescription drugs (SUPN) to spherical out the portfolio.
The healthcare fund is rebalanced and reconstituted quarterly to make sure traders have a foothold within the pharmaceutical shares that the numbers appear to be behind.
On the charts, PJP has managed to climb about 14% year-to-date.
Be taught extra about PJP on the Invesco supplier web site.

World X Telemedicine & Digital Well being ETF
- Belongings underneath administration: $623.6 million
- Dividend yield: 0.03%
- Bills: 0.68%
The World X Telemedicine & Digital Well being ETF (EDOC, $18.50) is without doubt one of the extra tactical healthcare ETFs on this listing. It does what the identify implies: put money into firms advancing the fields of digital healthcare. This encompasses companies concerned in every thing from telemedicine, healthcare “huge knowledge” and analytics, related gadgets, affected person file digitization and different related areas.
The fund’s high holdings embrace genetic diagnostics firm Illumina (ILMN), chromatography and spectrometry specialist Agilent Applied sciences (A) and high-tech diabetes monitoring agency Dexcom (DXCM) to call just a few. Significantly within the wake of the pandemic, it needs to be clear how necessary it’s to rapidly assess affected person wants and ship transportable digital information to the place they’re wanted.
EDOC has cooled off in a giant method since February now that the most important upswing brought on by the general public well being issues of 2020 are within the rearview. Nonetheless, long-term traders is likely to be on this healthcare ETF due to the alternatives these sorts of firms present past COVID-19.
Be taught extra about EDOC on the World X supplier web site.

Invesco S&P SmallCap Well being Care ETF
- Belongings underneath administration: $526.1 million
- Dividend yield: 0.00%
- Bills: 0.29%
Talking of long-term potential, the Invesco S&P SmallCap Well being Care ETF (PSCH, $191.11) is an alternative choice for traders who’re much less involved with the day-to-day volatility of healthcare shares and as a substitute desire a foothold in firms which may be increased danger, however might additionally ship increased rewards.
We’re speaking about shares like pharmacy automation agency Omnicell (OMCL), nurse and physician staffing software program operator AMN Healthcare Companies (AMN) and most cancers testing providers supplier NeoGenomics (NEO) to call just a few.
These shares are hardly the high-profile investments which are usually the mainstays of a typical portfolio. And since they collectively solely add as much as $18.Four billion in market worth, they’re additionally an important instance of firms with numerous headroom once they start firing on all cylinders.
And curiously sufficient, although just a few of the healthcare ETFs on this listing have been underneath stress within the final a number of months, PSCH has had an important run. The shares are up greater than 43% within the final 12 months to handily outperform the S&P 500 – in addition to most different healthcare sector funds. That is proof that going small doesn’t suggest you possibly can’t faucet into features, even when blue-chip healthcare shares hit a tough patch.
Be taught extra about PSCH on the Invesco supplier web site.
The views and opinions expressed herein are the views and opinions of the creator and don’t essentially replicate these of Nasdaq, Inc.
www.nasdaq.com